Cell Line Development Workflow

Solentim technology streamlines workflows in the creation isolation and characterization of high value cells in cell line development vaccine production cell and gene therapy.

Cell line development workflow.

Cell line development campaigns are typically performed over the course of several weeks to months at a time. This innovative offering is based on uga s well established platform technologies including their proprietary cho host cell lines system optimized expression vectors and. Single cells proliferate to form colonies that can then be assessed for. In cell line development cld you are looking for the rare high producing clones.

Cell line development cld on the beacon optofluidic system enables selection of the best production cell lines with 99 monoclonality assurance in just days. We accelerate cell line workflow timelines from upstream development through scale up to production of new biological therapies. The opto cld workflow screens thousands of clones with ease in less than a week. The uga biopharma gmbh high speed workflow was established as an improved cell line development workflow that guarantees cho cell line development on a shortened time scale.

The new opto cld 2 0 workflow extends these capabilities to allow 1 enrichment of rare cell populations 2 on chip titer measurements for traditional and non traditional antibody molecules and 3 efficient recovery. Based on the suretechnology platform and unique world class expertise selexis sure cell line development services significantly reduce the time effort and costs that are associated with the development of high performance mammalian cell lines for therapeutic protein production e g development of monoclonal antibodies bi specific monoclonal antibodies growth factors and enzymes. From vector design and host cell selection prior to transfection single cell cloning and colony outgrowth right through to the establishment of the master cell bank solentim technologies provide the evidence for. Cell line development is the process of establishing a clonally derived cell population which has been genetically engineered to express a desirable phenotype such as producing large amounts of recombinant protein for a stable period of time.

Cell line development workflow in order to generate high yields of recombinant protein products stable cell lines such as cho or hek 293 are typical vehicles of choice. The biomek software suite ensures data integrity to provide peace of mind and schedules activities to streamline each automated workflow. Typical cell line workflow.